Opioids

7 episodes

EduCastOpioidsPharmacologyPodcast

Ep 25 – DiaMorphine

Diamorphine for the FRCA Primary In this episode of Gas, Gas, Gas, we dive deep into the pharmacology of diamorphine also known by its more notorious street name, heroin. Diamorphine is a synthetic diacetylated derivative of morphine, and this episode details its mechanism of action, clinical applic

29 May 2025

EduCastOpioidsPharmacologyPodcast

Ep 25 – Oxycodone for the FRCA Primary

Introduction Oxycodone is a semi‑synthetic opioid widely used for moderate‑to‑severe acute and cancer‑related pain. Its higher oral bio‑availability and potency relative to morphine make it a common choice in peri‑operative analgesia, patient‑controlled analgesia (PCA) and palliative care, topics ex

22 May 2025

EduCastOpioidsPharmacologyPodcast

Ep 24 – Methadone for the FRCA Primary

In this episode of the GasGasGas, we learn about methadone for the FRCA primary exam, its pharmacology, diverse receptor activity, and relevance in both chronic pain and addiction management. While traditionally associated with managing opioid dependency, methadone’s unique pharmacodynamics an

10 May 2025

EduCastOpioidsPharmacologyPodcast

Ep 23 – Tramadol for the FRCA Primary Exam

Introduction In this episode of GasGasGas, primary FRCA podcast, we dissect Tramadol, a somewhat controversial yet commonly encountered analgesic. While some clinicians appreciate its multimodal action, others question its efficacy. Understanding its nuanced pharmacology is crucial for FRCA candidat

7 May 2025

EduCastOpioidsPharmacologyPodcast

Ep.22 – Alfentanil for the FRCA Primary

In this episode of GasGasGas, we explore the knowledge need re: Alfentanil for the FRCA primary exam, it is a short-acting μ-opioid receptor agonist that is ideal for anaesthetic practice. Discovered in 1976 by Janssen Pharmaceuticals, Alfentanil remains a valuable agent, especially for (modified) r

28 Apr 2025

EduCastOpioidsPharmacologyPodcast

Ep 15 – Morphine for the FRCA Primary Exam

Morphine for the FRCA Primary Exam This FRCA Primary Exam Podcast analyses Morphine, particularly the opiate receptors, mechanisms, pharmacokinetics and pharmacodynamics finishing up with clinical use. I appreciate that everyone is very familiar with Morphine, this creates two issues: So, I’ve been

22 Nov 2024

EduCastOpioidsPharmacologyPodcast

Ep 3 – Fentanyl For The FRCA Primary

We’re talking the core fentanyl waffle, and a jump into the opiate GPCRs. Closing up with some talk on using fentanyl in day to day practice. Very commonly used opiate, chief uses include as a co-induction agent for anaesthesia, perioperative pain control, post op pain control and as an elemen

8 Nov 2024