Vasopressin
Vasopressin (ADH) for the FRCA: V1, V2 and V3 receptors, terlipressin and desmopressin, and its role in catecholamine-refractory vasoplegic shock.
12 Oct 2026
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Anaesthetic Science — Straight Into Your Ears, Twice A Month!
- We want you to gain the knowledge easily, so you can learn the tricky bit of actually anaesthetising in the hospital
- VivaCast — how to answer SOE / viva questions, with willing victim Tom (who passed!)
- Pharmacology — exploring almost all anaesthetic drugs and their use
- Explainers on TCI, compartmental pharmacokinetics, and related critical concepts
- The future brings physiology, physics, and clinical equipment into the melange!
Recent Episodes
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Metaraminol for the FRCA Primary + indirect vs direct mechanisms
Introducing the string to your SVR management bow, Metaraminol, an alpha agonist of the mostly indirect variety, and why it fades as noradrenaline runs out
24 Aug 2026
Ephedrine
Ephedrine is a sympathomimetic drug used for mild peri-operative hypotension, acting directly and indirectly to stimulate the sympathetic nervous system
9 Aug 2026
Anticholinesterases For The Anaesthetically Adept
Anticholinesterases for FRCA: mechanism of action, neostigmine pharmacology, muscarinic side effects, organophosphate poisoning, and acetylcholine synthesis at the NMJ.
19 Apr 2026
Sugammadex For Anaesthetists
Sugammadex pharmacology for FRCA: mechanism, dosing by block depth, pharmacokinetics, anaphylaxis incidence, and the contraceptive interaction.
1 Apr 2026
Pancuronium For Anaesthetists
Pancuronium bromide: aminosteroid pharmacology, vagolytic cardiovascular effects, and Phase I vs Phase II neuromuscular blockade for FRCA preparation.
22 Mar 2026
Deep-Dive Chapters
Curated series Chapter Series
Opioids: Almost Everything You Need to Know
A deep-dive into opioid pharmacology for the Primary FRCA — mechanisms, PK/PD, and clinical use.
Chapter Series
Local Anaesthetics: Everything Your Brain Needs to Know
Mechanisms, structure, and clinical pharmacology of all LA drugs.
Chapter Series
Hypnotica: All of the Induction Drugs
Propofol, ketamine, thiopentone, etomidate — complete PK/PD and exam-ready.
Chapter Series
Comparing Volatile Anaesthetic Agents
Side-by-side pharmacology of sevoflurane, desflurane, and isoflurane.
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79 episodes
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